Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 9/20 | 0.35 |
| ▸ | PPARD | Q03181 | 9/20 | 0.35 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564132 | 0.90 | OPRD1 (0.43) | OPRD1OPRM1EPHX2NR1H4GAA | |
| SCHEMBL28913856 | 0.85 | OPRD1 (0.42) | OPRD1OPRM1EPHX2NR1H4GAA | |
| SCHEMBL28913855 | 0.85 | OPRD1 (0.42) | OPRD1OPRM1EPHX2NR1H4GAA | |
| SCHEMBL28220061 | 0.76 | NPC1 (0.43) | PPARGPPARAALDH1A1 | |
| SCHEMBL28563950 | 0.76 | ATM (0.42) | OPRD1OPRM1EPHX2NR1H4PPARG | |
| SCHEMBL29688160 | 0.76 | ATM (0.42) | OPRD1OPRM1EPHX2NR1H4PPARG | |
| SCHEMBL21447246 | 0.76 | ATM (0.42) | OPRD1OPRM1EPHX2NR1H4PPARG | |
| SCHEMBL28566530 | 0.76 | OPRD1 (0.42) | OPRD1OPRM1EPHX2NR1H4GAA | |
| SCHEMBL28566533 | 0.76 | OPRD1 (0.42) | OPRD1OPRM1EPHX2NR1H4GAA | |
| SCHEMBL23357298 | 0.76 | OPRD1 (0.58) | OPRD1OPRM1EPHX2NR1H4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867705-A | Opioid receptor modulators and products and methods related thereto | 埃皮欧黛公司 | 2021-05-28 | — | — | CN | disclosed |