Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 8/20 | 0.35 |
| ▸ | PPARD | Q03181 | 8/20 | 0.35 |
| ▸ | PPARA | Q07869 | 8/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566533 | 1.00 | OPRD1 (0.42) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL28913856 | 0.90 | OPRD1 (0.42) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL28913855 | 0.90 | OPRD1 (0.42) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL29162554 | 0.86 | DGAT1 (0.43) | OPRM1 | |
| SCHEMBL29162551 | 0.86 | DGAT1 (0.43) | OPRM1 | |
| SCHEMBL28564132 | 0.84 | OPRD1 (0.43) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL28545799 | 0.82 | DPP4 (0.40) | ALDH1A1 | |
| SCHEMBL30980849 | 0.79 | OPRD1 (0.45) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL16597372 | 0.75 | GAA (0.53) | OPRD1GAAOPRM1EPHX2NR1H4 | |
| SCHEMBL23357080 | 0.75 | MAPK1 (0.50) | OPRD1GAAOPRM1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867705-A | Opioid receptor modulators and products and methods related thereto | 埃皮欧黛公司 | 2021-05-28 | — | — | CN | disclosed |