SCHEMBL28564005

SCHEMBL28564005

OB(Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TRPV6 Q9H1D0 1/20 0.38
MGLL Q99685 1/20 0.38
PPARG P37231 4/20 0.36
PPARA Q07869 1/20 0.36
P2RX1 P51575 1/20 0.36
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
TACR1 P25103 5/20 0.35
TLR8 Q9NR97 1/20 0.33
MAPT P10636 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
CACNA1F O60840 1/20 0.33
CACNA1D Q01668 1/20 0.33
CACNA1S Q13698 1/20 0.33
CACNA1C Q13936 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28493928 0.83 TRPV6 (0.42) ALDH1A1TSHRTRPV6MGLLPPARG
SCHEMBL6249074 0.81 CA1 (0.35) ALDH1A1TSHRTRPV6
Ammonia Solution, Strong SCHEMBL6251034 0.80 CA1 (0.34) ALDH1A1TSHR
SCHEMBL4444280 0.79 CES2 (0.41) TRPV6MGLLIDO1TLR8MAPT
SCHEMBL28506350 0.76 TRPV6 (0.36) ALDH1A1TSHRTRPV6MGLLPPARG
SCHEMBL2801163 0.76 TACR1 (0.42) ALDH1A1TRPV6TACR1KDM4E
SCHEMBL5400406 0.76 TACR1 (0.42) ALDH1A1TRPV6TACR1KDM4E
Benzene SCHEMBL28493930 0.76 IDO1 (0.40) ALDH1A1TSHRTRPV6MGLLPPARG
SCHEMBL17583792 0.76 IDO1 (0.41) ALDH1A1TSHRTRPV6MGLLPPARG
SCHEMBL28419769 0.75 KIF11 (0.40) ALDH1A1TSHRTRPV6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423744-A Lewis base catalyst and process therefor 埃克森美孚化学专利公司 2021-09-21 CN disclosed
CN-112912357-A Process and apparatus for producing poly-alpha-olefin terpolymer 埃克森美孚化学专利公司 2021-06-04 CN disclosed