Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | CPA2 | P48052 | 1/20 | 0.37 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972235 | 1.00 | ALDH1A1 (0.47) | ALDH1A1PLA2G10PLA2G2CCTSSSIRT6 | |
| SCHEMBL4367034 | 0.99 | ALDH1A1 (0.46) | ALDH1A1PLA2G10PLA2G2CCTSSSIRT6 | |
| SCHEMBL7325484 | 0.86 | PLA2G10 (0.43) | PLA2G10CTSSMMP3PLA2G2APLA2G5 | |
| SCHEMBL7333517 | 0.85 | PLA2G10 (0.58) | PLA2G10PLA2G2CPLA2G2APLA2G5 | |
| SCHEMBL7371455 | 0.83 | CAPN1 (0.42) | PLA2G10CTSSBIRC2CTSLCTSK | |
| SCHEMBL7376759 | 0.83 | PLA2G10 (0.60) | PLA2G10PLA2G2CPLA2G2APLA2G5 | |
| SCHEMBL7335388 | 0.83 | PLA2G10 (0.60) | PLA2G10PLA2G2CPLA2G2APLA2G5 | |
| SCHEMBL21387168 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CTSSSIRT6SIRT1MMP3 | |
| SCHEMBL9064502 | 0.82 | PLA2G10 (0.48) | PLA2G10PLA2G2CMMP3PLA2G2APLA2G5 | |
| SCHEMBL7335551 | 0.81 | CTSK (0.53) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112870358-B | Use of deubiquitinase USP20 for reducing cholesterol synthesis and improving metabolic syndrome | 武汉大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-112870358-A | Use of deubiquitinase USP20 for reducing cholesterol synthesis and improving metabolic syndrome | 武汉大学 | 2021-06-01 | — | — | CN | disclosed |