Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333517 | 0.88 | PLA2G10 (0.58) | PLA2G10PSMB5PLA2G2APLA2G5 | |
| SCHEMBL7335388 | 0.86 | PLA2G10 (0.60) | PLA2G10PSMB5PLA2G2APLA2G5 | |
| SCHEMBL7376759 | 0.86 | PLA2G10 (0.60) | PLA2G10PSMB5PLA2G2APLA2G5 | |
| SCHEMBL8972235 | 0.86 | ALDH1A1 (0.47) | PLA2G10BIRC2CTSSMMP3MMP9 | |
| SCHEMBL28564205 | 0.86 | ALDH1A1 (0.47) | PLA2G10BIRC2CTSSMMP3MMP9 | |
| SCHEMBL4367034 | 0.84 | ALDH1A1 (0.46) | PLA2G10BIRC2CTSSMMP3MMP9 | |
| SCHEMBL7328537 | 0.82 | HDAC2 (0.48) | MMEBIRC2MMP3MMP9REN | |
| SCHEMBL7371455 | 0.81 | CAPN1 (0.42) | PLA2G10BIRC2CTSSPSMB5 | |
| SCHEMBL9064502 | 0.80 | PLA2G10 (0.48) | PLA2G10BIRC2MMP3MMP9PLA2G2A | |
| SCHEMBL7327504 | 0.80 | CTSK (0.54) | PLA2G10BIRC2CTSSPSMB5MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510531-A | ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS | SUNTORY LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0393457-B1 | Proteinase inhibitor | SUNTORY LTD (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5081284-A | N-Oxomethyl-Substituted Peptide | SUNTORY LIMITED (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0393457-A1 | Proteinase inhibitor | SUNTORY LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |