Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.77 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951299 | 0.87 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL13978663 | 0.87 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29529294 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29958044 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKMT2A | |
| SCHEMBL29956322 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29954829 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBCYP19A1 | |
| SCHEMBL1861100 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBCYP19A1 | |
| SCHEMBL19182133 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29757393 | 0.79 | PTPN1 (0.66) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL26611784 | 0.79 | PTPN1 (0.66) | PTPN1PTPN2MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-105820165-B | Alpha-carboline compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-05-04 | — | — | CN | disclosed |