Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 6/20 | 0.60 |
| ▸ | MAOB | P27338 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911098 | 0.87 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29952420 | 0.87 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL15329656 | 0.84 | CYP3A4 (0.52) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL15329654 | 0.84 | CYP3A4 (0.52) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL19182133 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29529294 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29954829 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29958044 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL28564467 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL1861100 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |