Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954829 | 1.00 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL13080558 | 0.88 | KDM4E (0.50) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL23707495 | 0.87 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL28564467 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29529294 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29956322 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL19182133 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29958044 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL30705195 | 0.79 | XDH (0.74) | MAOAMAOBKDM4EALDH1A1NPC1 | |
| SCHEMBL11412845 | 0.79 | KDM4E (0.65) | MAOAMAOBKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984441-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
| CN-115246805-B | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-01-19 | — | — | CN | disclosed |
| US-20230270663-A1 | FORMULATION FOR THE TREATMENT OF FINE LINES AND WRINKLES AND USES THEREOF | BAIN CAPITAL CREDIT, LP, AS COLLATERAL AGENT | 2023-08-31 | — | — | US | disclosed |
| US-20230270663-A1 | FORMULATION FOR THE TREATMENT OF FINE LINES AND WRINKLES AND USES THEREOF | BAIN CAPITAL CREDIT, LP, AS COLLATERAL AGENT | 2023-08-31 | — | — | US | disclosed |
| CN-115246805-A | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2022-10-28 | — | — | CN | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| EP-1508327-B1 | Use of 5,7-dihydroxy-2-methylchromen-4-on for the care of the skin | MERCK PATENT GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8518986-B2 | Compositions containing retinoid and chromenone derivatives | JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) | 2013-08-27 | — | — | US | disclosed |
| US-8518986-B2 | Compositions containing retinoid and chromenone derivatives | JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) | 2013-08-27 | — | — | US | disclosed |
| US-20090209637-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209637-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-20 | — | — | US | disclosed |
| EP-1979337-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | Merck Patent GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| EP-1946798-A1 | Compositions containing retinoid and chromenone derivatives | Johnson & Johnson Consumer France SAS (FR) | 2008-07-23 | — | — | EP | disclosed |
| WO-2008025368-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-03-06 | — | — | WO | disclosed |
| US-20080027133-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | CAROLA CHRISTOPHE | 2008-01-31 | — | — | US | disclosed |
| US-20080027133-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | CAROLA CHRISTOPHE | 2008-01-31 | — | — | US | disclosed |
| US-20070191305-A1 | Chromone complexes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191305-A1 | Chromone complexes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-16 | — | — | US | disclosed |
| WO-2007087956-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209637-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | CBR1, CYP46A1, CCR8 | PTPN1 3158/4885PTPN2 3248/4885MAOA 562/4885 |
| US-20230270663-A1 | FORMULATION FOR THE TREATMENT OF FINE LINES AND WRINKLES AND USES THEREOF | CUTA, RXRA, RARA | PTPN1 3453/4885PTPN2 3189/4885MAOA 919/4885 |
| US-20070191305-A1 | Chromone complexes | SCO2, CDYL, CYCS | PTPN1 2872/4885PTPN2 2757/4885MAOA 1176/4885 |
| US-20080027133-A1 | USE OF CHROMEN-4-ONE DERIVATIVES | CYP8B1, CYP7B1, CYP2R1 | PTPN1 3642/4885PTPN2 3732/4885MAOA 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.