Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861100 | 1.00 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL13080558 | 0.88 | KDM4E (0.50) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL23707495 | 0.87 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29958044 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL28564467 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL19182133 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29529294 | 0.80 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL29956322 | 0.80 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBKDM4E | |
| SCHEMBL30705195 | 0.79 | XDH (0.74) | MAOAMAOBKDM4EALDH1A1NPC1 | |
| SCHEMBL11412845 | 0.79 | KDM4E (0.65) | MAOAMAOBKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |