Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.58 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975125 | 0.93 | THRA (0.53) | SMPD1FPR2PTPN11GAKPTPN1 | |
| SCHEMBL13957128 | 0.91 | PTPN11 (0.55) | SMPD1FPR2PTPN11PTPN1PTPN6 | |
| SCHEMBL28319408 | 0.91 | PTPN11 (0.55) | SMPD1FPR2PTPN11PTPN1PTPN6 | |
| SCHEMBL1776071 | 0.91 | PTPN11 (0.55) | SMPD1FPR2PTPN11PTPN1PTPN6 | |
| SCHEMBL2856448 | 0.91 | PTPN11 (0.55) | SMPD1FPR2PTPN11PTPN1PTPN6 | |
| SCHEMBL9483679 | 0.83 | MGLL (0.55) | SMPD1PTPN11PTPN1PTPN6 | |
| SCHEMBL24305898 | 0.83 | SMPD1 (0.56) | SMPD1PDE4BPRSS1 | |
| SCHEMBL9698395 | 0.83 | SMPD1 (0.59) | SMPD1PDE4BPRSS1 | |
| SCHEMBL8974024 | 0.83 | PTPN11 (0.57) | FPR2PTPN11PDE4BPDE4APDE4C | |
| SCHEMBL8974122 | 0.83 | SMPD1 (0.56) | SMPD1PDE4BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703885-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029243-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |