Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856448 | 0.88 | PTPN11 (0.55) | PTPN11SMPD1ALDH1A1HPGDPTPN1 | |
| SCHEMBL13957128 | 0.88 | PTPN11 (0.55) | PTPN11SMPD1ALDH1A1HPGDPTPN1 | |
| SCHEMBL28319408 | 0.88 | PTPN11 (0.55) | PTPN11SMPD1ALDH1A1HPGDPTPN1 | |
| SCHEMBL1776071 | 0.88 | PTPN11 (0.55) | PTPN11SMPD1ALDH1A1HPGDPTPN1 | |
| SCHEMBL13527508 | 0.86 | PTPN11 (0.44) | PTPN11SMPD1TLR8ALDH1A1HPGD | |
| SCHEMBL13527506 | 0.86 | MAOB (0.51) | PTPN11TLR8THRATHRBALDH1A1 | |
| SCHEMBL6737580 | 0.84 | PTPN11 (0.44) | PTPN11SMPD1TLR8PTPN1PTPN6 | |
| SCHEMBL8975125 | 0.83 | THRA (0.53) | PTPN11SMPD1THRATHRBPTPN1 | |
| SCHEMBL8974024 | 0.80 | PTPN11 (0.57) | PTPN11TLR8THRATHRBPTPN1 | |
| SCHEMBL676845 | 0.80 | SMPD1 (0.51) | PTPN11SMPD1TLR8THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437123-B1 | NEMATIC DISCOTIC LIQUID CRYSTAL PHASE, A COLUMNAR LIQUID CRYSTAL PHASE AND/OR A COLUMNAR CRYSTALLINE PHASE; ELECTRON-DEFICIENT CENTRAL UNIT THAT FAVOURS TRANSPORT OF ELECTRONS, ELECTROLUMINESCENT | SHARP KABUSHIKI KAISHA (JP) | 2002-08-20 | — | — | US | disclosed |