Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564659 | 1.00 | LDHA (0.34) | LDHACTBP2MAPK1SMN1; SMN2TPH1 | |
| SCHEMBL22723020 | 0.89 | LDHA (0.37) | LDHATPH1PPARGPPARASLC6A4 | |
| SCHEMBL22723021 | 0.89 | LDHA (0.37) | LDHATPH1PPARGPPARASLC6A4 | |
| SCHEMBL28562308 | 0.89 | SCN9A (0.35) | LDHACTBP2MAPK1SMN1; SMN2TPH1 | |
| SCHEMBL18262541 | 0.81 | LDHA (0.36) | LDHACTBP2ALDH1A1KDM4EACACB | |
| SCHEMBL18262546 | 0.81 | LDHA (0.36) | LDHACTBP2ALDH1A1KDM4EACACB | |
| SCHEMBL18262544 | 0.81 | LDHA (0.36) | LDHACTBP2ALDH1A1KDM4EACACB | |
| SCHEMBL28562309 | 0.79 | ITGB3 (0.44) | PPARGPPARAALDH1A1 | |
| SCHEMBL28558404 | 0.79 | ALDH1A1 (0.36) | LDHASMN1; SMN2PPARGPPARAPPARD | |
| SCHEMBL18262421 | 0.73 | LDHA (0.39) | LDHAALDH1A1KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |