SCHEMBL28564772

SCHEMBL28564772

C=Cc1ccc(Cl)cc1CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 1/20 0.35
GABRA1 P14867 3/20 0.33
GABRB2 P47870 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PNMT P11086 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
MEN1 O00255 1/20 0.33
SLC22A1 O15245 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
HSP90AA1 P07900 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HSPD1 P10809 1/20 0.33
HSPA5 P11021 1/20 0.33
IDO1 P14902 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16241052 0.80 GABRA1 (0.55) SLC6A2GABRA1GABRB2TDP1MEN1
SCHEMBL11027744 0.80 ALDH1A1 (0.35) GABRA1GABRB2TDP1GABRG2GABRB3
SCHEMBL15524757 0.79 HPGD (0.36) SLC6A2SLC6A4TDP1MEN1SLC22A1
SCHEMBL8170934 0.79 TDP1 (0.41) SLC6A2SLC6A4TDP1MEN1SLC22A1
SCHEMBL809863 0.78 HTR2A (0.31) SLC6A2SLC6A4TDP1MEN1SLC22A1
SCHEMBL810176 0.77 HPGD (0.38) TDP1MEN1SLC22A1USP2LMNA
SCHEMBL809517 0.77 S1PR1 (0.31) TDP1MEN1SLC22A1USP2LMNA
SCHEMBL29135543 0.76 PTGDR (0.47) GABRA1GABRB2TDP1MEN1SLC22A1
SCHEMBL5018843 0.75 SLC6A2 (0.45) SLC6A2SLC6A4GABRA1GABRB2TDP1
SCHEMBL30641415 0.73 GABRA1 (0.47) SLC6A2SLC6A4GABRA1GABRB2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112824432-B Polymerizable fluorene photoinitiator, photocurable composition containing same and application thereof 常州强力电子新材料股份有限公司 2023-05-02 CN disclosed
CN-112824432-A Polymerizable fluorene photoinitiator, photocuring composition containing polymerizable fluorene photoinitiator and application of polymerizable fluorene photoinitiator 常州强力电子新材料股份有限公司 2021-05-21 CN disclosed