Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857758 | 0.89 | TRPV1 (0.41) | MAPK1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2857979 | 0.87 | TRPV1 (0.39) | MAPK1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2850556 | 0.87 | KDM4E (0.41) | RAB9ANPC1KDM4EFFAR4CNR1 | |
| SCHEMBL2857936 | 0.86 | KDM4E (0.47) | MAPK1KMT2ATRPV1HIF1AKDM4E | |
| SCHEMBL2854553 | 0.85 | TRPV1 (0.39) | MAPK1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2848513 | 0.85 | P2RX7 (0.43) | MAPK1TRPV1HIF1AKDM4ESCN9A | |
| SCHEMBL2859594 | 0.84 | TAAR1 (0.45) | MEN1KMT2AKDM4ETAAR1FFAR4 | |
| SCHEMBL2860303 | 0.84 | TRPV1 (0.39) | RAB9ANPC1TRPV1KDM4ESCN9A | |
| SCHEMBL2858012 | 0.83 | CNR1 (0.46) | MAPK1TRPV1HIF1AKDM4ETAAR1 | |
| SCHEMBL2857357 | 0.78 | HTT (0.46) | MAPK1MEN1KMT2AGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |