Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856479 | 0.87 | MAPK1 (0.41) | TRPV1MAPK1CNR1HIF1ANPC1 | |
| SCHEMBL2854467 | 0.86 | MAPT (0.36) | TRPV1CNR1KDM4ETAAR1 | |
| SCHEMBL2850252 | 0.86 | TRPV1 (0.40) | TRPV1CNR1SCN9AKDM4ERXFP1 | |
| SCHEMBL2858012 | 0.85 | CNR1 (0.46) | TRPV1MAPK1CNR1HIF1AKDM4E | |
| SCHEMBL2859504 | 0.85 | TAAR1 (0.43) | TRPV1CNR1NPC1RAB9AMEN1 | |
| SCHEMBL2857936 | 0.85 | KDM4E (0.47) | TRPV1MAPK1HIF1AKMT2AKDM4E | |
| SCHEMBL2854553 | 0.84 | TRPV1 (0.39) | TRPV1MAPK1CNR1HIF1ANPC1 | |
| SCHEMBL2857758 | 0.84 | TRPV1 (0.41) | TRPV1MAPK1HIF1ANPC1RAB9A | |
| SCHEMBL2848513 | 0.83 | P2RX7 (0.43) | TRPV1MAPK1HIF1ASCN9AKDM4E | |
| SCHEMBL2853347 | 0.79 | TRPV1 (0.41) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |