Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564924 | 0.92 | MAPT (0.55) | TSHRMAOBMAPTNPSR1MAOA | |
| SCHEMBL28557828 | 0.90 | MAPT (0.54) | TSHRMAOBMAPTNPSR1MAOA | |
| SCHEMBL28566805 | 0.85 | FKBP1A (0.60) | TSHRMAOBMAPTNPSR1LMNA | |
| SCHEMBL8282265 | 0.84 | MAPT (0.58) | TSHRMAPTNPSR1LMNAGAA | |
| SCHEMBL28363239 | 0.81 | LMNA (0.56) | TSHRMAOBMAPTNPSR1LMNA | |
| SCHEMBL2926027 | 0.81 | TSHR (0.71) | TSHRMAOBMAPTMAOAFKBP1A | |
| SCHEMBL107322 | 0.81 | MAOB (0.83) | TSHRMAOBMAPTMAOAFKBP1A | |
| SCHEMBL5384858 | 0.80 | TSHR (0.57) | TSHRMAOBMAPTNPSR1LMNA | |
| SCHEMBL26250266 | 0.80 | TSHR (0.57) | TSHRMAOBMAPTNPSR1LMNA | |
| SCHEMBL1744782 | 0.80 | RAB9A (0.66) | TSHRMAPTNPSR1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407801-B | 3, 4-methylenedioxy phenoxy fibrate- (3, 4-methylenedioxy) phenyl ester compound and application thereof in reducing blood fat | 陕西中医药大学 | 2020-12-22 | — | — | CN | disclosed |