SCHEMBL28565

SCHEMBL28565

NC([O])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27636065 0.94
Carbamic Acid SCHEMBL1356882 0.80
Carbamic Acid SCHEMBL9174045 0.80 ACHE (0.88)
Urea SCHEMBL347768 0.80
Urea SCHEMBL8560069 0.77 LMNA (1.00)
Urea SCHEMBL411583 0.77
Urea SCHEMBL8436158 0.77 LMNA (1.00)
Urea SCHEMBL7756359 0.77 LMNA (1.00)
Urea SCHEMBL8434002 0.77 LMNA (1.00)
Urea SCHEMBL20641124 0.77 LMNA (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 29329 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US claimed
WO-2024151759-A1 HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS SYNNOVATION THERAPEUTICS, INC. (US) 2024-07-18 WO claimed
EP-4399527-A1 A METHOD OF DETERMINING THE PRESENCE OF AN ANALYTE IN A SAMPLE Valitacell Limited (IE) 2024-07-17 EP claimed
CN-118340754-A Compound for treating heart failure and related diseases and application thereof 源道医药(苏州)有限公司 2024-07-16 CN claimed
US-20240228785-A1 Fluorogenic pH-Sensitive Compounds and Their Methods of Use Life Technologies Corporation 2024-07-11 US claimed
EP-4396187-A1 NAPHTHYRIDINE COMPOUNDS AS INHIBITORS OF KRAS Incyte Corporation (US) 2024-07-10 EP claimed
US-12030883-B2 Hetero-tricyclic compounds as inhibitors of KRAS INCYTE CORPORATION (US) 2024-07-09 US claimed
CN-118239868-A Carbamate substituted styryl sulfone compound and preparation method and application thereof 华夏生生药业(北京)有限公司 2024-06-25 CN claimed
US-12012409-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2024-06-18 US claimed
CN-112512529-B Cyclopentenepurine derivative or salt thereof 富士胶片株式会社 2024-06-18 CN claimed
US-4003914-A DITHIANE AND DISULFONE CORONARY DILATING AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-01-18 US claimed
US-RE29119-E 7-Pyridinium methyl carboxyl derivatives of 7-amino-cephalosporanic acid CIBA-GEIGY CORPORATION (US) 1977-01-18 US claimed
US-4000253-A FUNGICIDES, BACTERICIDES, ALGICIDES STAUFFER CHEMICAL COMPANY (US) 1976-12-28 US claimed
US-3994885-A WITH ALKALI METAL ALKOXIDE, HALOGENATION ELI LILLY AND COMPANY (US) 1976-11-30 US claimed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US claimed
US-3980644-A EXTRACTION WITH CYCLOHEXANONE ELI LILLY AND COMPANY (US) 1976-09-14 US claimed
US-3980632-A SYNTHETIC MATERIALS, LEATHER, PAPER, PIGMENTING PLASTICS SANDOZ LTD. (CH) 1976-09-14 US claimed
US-3966797-A Dinorbornenes UNION CARBIDE CORPORATION (US) 1976-06-29 US claimed
US-3962224-A CHEMICAL INTERMEDIATES FOR ANTIBIOTICS MERCK & CO., INC. (US) 1976-06-08 US claimed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US claimed