Urea

Urea

SCHEMBL347768

NC(N)=O.O=C(O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL15313325 0.94 LMNA (0.67)
Carbamic Acid SCHEMBL6258349 0.94 ACHE (0.78)
Urea SCHEMBL15313330 0.94
Urea SCHEMBL10625073 0.94
Urea SCHEMBL9700038 0.94
Urea SCHEMBL23387647 0.94
Urea SCHEMBL1439370 0.94
Urea SCHEMBL42148 0.94
Urea SCHEMBL2473758 0.94 LMNA (0.86)
Urea SCHEMBL10800403 0.89 LMNA (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625189-B1 DEFOAMER EMULSION BASF SE (DE) 2025-02-12 EP claimed
CN-113265186-B Flame-retardant molecular chain grafted mesoporous silica modified epoxy resin coating and preparation method thereof 深圳市锦旺兴绝缘材料有限公司 2022-06-24 CN claimed
CN-113546040-A Carbamide peroxide non-aqueous solvent injection, preparation method and application 柯铭清 2021-10-26 CN claimed
CN-113265186-A Flame-retardant molecular chain grafted mesoporous silica modified epoxy resin coating and preparation method thereof 深圳市华必达科技有限公司 2021-08-17 CN claimed
EP-2890305-B1 MONO-LAYER THIN FILM ADHESIVE COMPOUNDS DSM IP ASSETS BV (NL) 2020-05-27 EP claimed
CN-106378131-B A kind of catalyst and preparation method thereof of alcoholysis of urea carbonate synthesis ester 青海金硕化工科技有限公司 2019-05-14 CN claimed
US-10238767-B2 Mono-layer thin film adhesive compounds and methods of synthesis and use DSM IP ASSETS, B.V. (NL) 2019-03-26 US claimed
EP-3368582-A1 POLYURETHANE/UREA MATERIALS Commonwealth Scientific and Industrial Research Organisation (AU) 2018-09-05 EP claimed
WO-2017070743-A1 POLYURETHANE/UREA MATERIALS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-05-04 WO claimed
EP-2890305-A1 MONO-LAYER THIN FILM ADHESIVE COMPOUNDS KNC NER Acquisition Sub, Inc. (US) 2015-07-08 EP claimed
US-20120016390-A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER ACQUISITION SUB, INC. (US) 2012-01-19 US claimed
US-20050128425-A1 High refractive index aromatic-based prepolymers SALIX PHARMACEUTICALS, LTD. 2005-06-16 US claimed
US-6599456-B1 Method and apparatus for the continuous and discontinuous production of boards of ligneous material MASCHINENFABRIK J. DIEFFENBACHER GMBH & CO (DE) 2003-07-29 US claimed
US-20030020054-A1 FLAME RETARDANT COMPOSITIONS UTILIZING AMINO CONDENSATION COMPOUNDS BLOUNT DAVID H (US) 2003-01-30 US claimed
US-20020173565-A1 Urea condensate fertilizer, fungicide and insecticide compositions BLOUNT DAVID H (US) 2002-11-21 US claimed
US-6348526-B1 FIREPROOFING WITH UREA POLYMERS BLOUNT DAVID H (US) 2002-02-19 US claimed
US-6270694-B1 PRODUCT FROM REACTED UREA, ORGANIC COMPOUND, WATER, CARBONIZATION AUXILIARIES, ALDEHYDE AND FILLER BLOUNT DAVID H (US) 2001-08-07 US claimed
US-6258298-B1 REDUCING COMBUSTIBILITY OF ORGANIC MATERIAL COMPRISING INCORPORATING AND AMINO CONDENSATION COMPOUND AND/OR COMPOSITION WITH THE ORGANIC MATERIAL, UNDER REACTION AND/OR MIXING CONDITIONS OF THE ORGANIC MATERIAL BLOUNT DAVID H (US) 2001-07-10 US claimed
US-5788915-A Flame retardant compositions utilizing partially hydrolyzed amino condensation compounds BLOUNT DAVID H (US) 1998-08-04 US claimed
US-5496454-A Method for the operation of electrolytic baths to produce Fe3 O4 electrophoretically in a three compartment cell UNITIKA LTD. (JP) 1996-03-05 US claimed