Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | CBS | P35520 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574425 | 0.90 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL28549950 | 0.83 | PPARA (0.44) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL28554455 | 0.82 | BCL2L1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL24703960 | 0.82 | BCL2L1 (0.60) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28554391 | 0.80 | MAPT (0.64) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL11957598 | 0.79 | MAPT (0.72) | MEN1KMT2AALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL2104937 | 0.77 | CBS (0.69) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28564785 | 0.77 | POLB (0.64) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28549966 | 0.76 | POLB (0.80) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28558394 | 0.76 | LMNA (0.52) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |