Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055159 | 0.88 | LMNA (0.47) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL28565247 | 0.82 | PDE2A (0.49) | LMNATSHRPDE2ACYP3A4CYP2C19 | |
| SCHEMBL8908712 | 0.82 | LMNA (0.45) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL7755747 | 0.81 | ALDH1A1 (0.40) | LMNATSHRADRB2ADRB1CYP2D6 | |
| SCHEMBL5107130 | 0.80 | LMNA (0.61) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL5107136 | 0.80 | LMNA (0.61) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL5107133 | 0.80 | LMNA (0.61) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL30172716 | 0.80 | LMNA (0.61) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL3998220 | 0.78 | LMNA (0.41) | LMNATSHRADRB2ADRB1PDE2A | |
| SCHEMBL984756 | 0.74 | TSHR (0.47) | LMNATSHRNFKB1HIF1ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504433-B1 | LAMINATED FILM AND PRODUCTION THEREOF | DAICEL CHEM (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5578372-A | Heat-weldable composite films and method of production thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0504433-A1 | LAMINATED FILM AND PRODUCTION THEREOF | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |