Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PDE6D | O43924 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20735193 | 0.91 | ALDH1A1 (0.82) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL20735205 | 0.85 | ALDH1A1 (0.74) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL20735204 | 0.85 | ALDH1A1 (0.74) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL299841 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL22203791 | 0.83 | POLB (0.64) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL1974304 | 0.83 | KMT2A (0.64) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL25335143 | 0.82 | ALDH1A1 (0.70) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL10792923 | 0.82 | POLB (0.70) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL18566560 | 0.82 | ALDH1A1 (0.70) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL30553977 | 0.82 | KMT2A (0.70) | ALDH1A1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658862-B | Sensor molecule based on naphthalimide derivative and synthesis and application thereof | 西北师范大学 | 2021-05-04 | — | — | CN | disclosed |