SCHEMBL1974304

SCHEMBL1974304

Nc1ccc(N2C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.64
MEN1 O00255 3/20 0.64
SCN2A Q99250 4/20 0.61
CA9 Q16790 3/20 0.61
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
ALDH1A1 P00352 3/20 0.59
RAB9A P51151 2/20 0.59
NPC1 O15118 1/20 0.59
TSHR P16473 1/20 0.59
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59
HSD17B10 Q99714 1/20 0.59
HSPA1A P0DMV8 1/20 0.56
PABPC1 P11940 1/20 0.56
ADORA2A P29274 1/20 0.56
NR1H3 Q13133 1/20 0.53
GAA P10253 1/20 0.53
CYP3A4 P08684 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10473743 0.89 NR1H3 (0.57) KMT2AMEN1SCN2ACA9CA12
SCHEMBL10475108 0.89 KMT2A (0.57) KMT2AMEN1SCN2ACA9CA12
SCHEMBL4649471 0.89 KMT2A (0.78) KMT2AMEN1SCN2ACA9CA12
SCHEMBL9566650 0.83 CASP1 (0.83) KMT2AMEN1CA9CA12CA1
SCHEMBL28565249 0.83 ALDH1A1 (0.70) KMT2AMEN1CA9CA12CA1
SCHEMBL9566604 0.83 HSPA1A (0.77) KMT2AMEN1SCN2ACA9CA12
SCHEMBL22203791 0.83 POLB (0.64) KMT2AMEN1SCN2ACA9CA12
SCHEMBL9277245 0.82 KMT2A (0.69) KMT2AMEN1SCN2ACA9CA12
N-Phenyl-Phthalimide SCHEMBL123618 0.81 KMT2A (0.68) KMT2AMEN1SCN2ACA9CA12
SCHEMBL19773976 0.81 KMT2A (0.68) KMT2AMEN1SCN2ACA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108605-A Method for preparing p-phenylenediamine from aniline 中国科学院大连化学物理研究所 2024-05-31 CN claimed
CN-118108604-A Method for preparing p-phenylenediamine by ammoniation of aniline 中国科学院大连化学物理研究所 2024-05-31 CN disclosed
CN-118108605-A Method for preparing p-phenylenediamine from aniline 中国科学院大连化学物理研究所 2024-05-31 CN disclosed
CN-111606850-B Preparation method of bedaquiline and intermediate thereof 安徽贝克生物制药有限公司 2023-07-25 CN disclosed
CN-110628025-B Polyimide precursor, polyimide, and material for use in production thereof 宇部兴产株式会社 2022-07-12 CN disclosed
CN-111606850-A Preparation method of bedaquiline and intermediate thereof 安徽贝克生物制药有限公司 2020-09-01 CN disclosed
CN-110628025-A Polyimide precursor, polyimide, and material for use in preparation thereof 宇部兴产株式会社 2019-12-31 CN disclosed
EP-2934536-A1 FACTOR IXa INHIBITORS Merck Sharp & Dohme Corp. (US) 2015-10-28 EP disclosed
WO-2014099694-A1 FACTOR IXa INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-06-26 WO disclosed
US-8524721-B2 Platelet ADP receptor inhibitors PORTOLA PHARMACEUTICALS, INC. (US) 2013-09-03 US disclosed
EP-0198082-B1 POLARIZING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-15 EP disclosed
EP-0482508-A1 Biscationic azo dyes and their intermediates BASF Aktiengesellschaft (DE) 1992-04-29 EP disclosed
US-5059356-A Hydrophobic polyethylene terephthalate containing a dichroic organic colorant substantially insoluble in water and solvents MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-10-22 US disclosed
US-4824882-A HYDROPHOBIC POLYMER CONTAINING DICHRIOC ORGANIC COLORANT MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-04-25 US disclosed
EP-0198082-A1 POLARIZING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-10-22 EP disclosed
EP-0015570-B1 ISOINDOLIN PIGMENTS AND THEIR USE BASF Aktiengesellschaft (DE) 1982-12-22 EP disclosed
US-4356123-A YELLOW PIGMENT BASF AKTIENGESELLSCHAFT (DE) 1982-10-26 US disclosed
US-4281100-A Injection moldable polyetherimide oligomers and method for making GENERAL ELECTRIC COMPANY (US) 1981-07-28 US disclosed
EP-0015570-A1 Isoindolin pigments and their use BASF Aktiengesellschaft (DE) 1980-09-17 EP disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed