Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659012 | 0.87 | RAB9A (0.52) | MAPTALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL29661164 | 0.87 | ALDH1A1 (0.71) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL2344119 | 0.87 | ALDH1A1 (0.71) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL11513071 | 0.86 | EPHX1 (0.69) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL15135742 | 0.85 | NPC1 (0.61) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL11515049 | 0.84 | PLK1 (0.65) | MAPTALDH1A1ALOX12RAB9ANPC1 | |
| SCHEMBL28557009 | 0.83 | NPC1 (0.58) | MAPTALDH1A1SMN1; SMN2ALOX12RAB9A | |
| SCHEMBL2342014 | 0.82 | ALDH1A1 (0.72) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL12316692 | 0.80 | AKT1 (0.55) | MAPTALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL2344788 | 0.79 | KMT2A (0.68) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112807294-B | Application of acyl thiourea compound in preparation of medicines for treating or preventing herpes simplex virus type I infection | 武汉大学 | 2023-09-05 | — | — | CN | claimed |
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | claimed |
| CN-112807294-A | Application of acylthiourea compound in preparation of medicine for treating or preventing herpes simplex virus I-type infection | 武汉大学 | 2021-05-18 | — | — | CN | claimed |
| CN-112807294-B | Application of acyl thiourea compound in preparation of medicines for treating or preventing herpes simplex virus type I infection | 武汉大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-110478344-B | Application of acylthiourea compound in preparation of anti-influenza B virus medicine | 武汉大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-113582969-B | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-110483425-B | Acyl thiourea compound, preparation method thereof and application of acyl thiourea compound in resisting influenza A virus | 武汉大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-112807294-A | Application of acylthiourea compound in preparation of medicine for treating or preventing herpes simplex virus I-type infection | 武汉大学 | 2021-05-18 | — | — | CN | disclosed |