Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510824 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2ITGB1ITGA4RAB9ANPC1 | |
| SCHEMBL3628702 | 0.77 | P2RX4 (0.46) | SMN1; SMN2BCHEKMT2AMEN1LMNA | |
| SCHEMBL28245942 | 0.76 | HDAC3 (0.43) | SMN1; SMN2BCHEKMT2A | |
| SCHEMBL16268685 | 0.76 | P2RX4 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1BCHE | |
| Hydrochloric Acid SCHEMBL7562002 | 0.76 | HDAC3 (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL991577 | 0.75 | HDAC3 (0.42) | SMN1; SMN2BCHEKMT2A | |
| SCHEMBL6168375 | 0.75 | HSD17B3 (0.49) | RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16268687 | 0.74 | NAMPT (0.47) | BCHE | |
| SCHEMBL4420044 | 0.74 | NAMPT (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3926713 | 0.73 | SDCBP (0.43) | SMN1; SMN2KMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142656-B | Sulfonyl pyridine amide derivatives and preparation method thereof | 杭州职业技术学院 | 2022-03-18 | — | — | CN | disclosed |
| CN-112142656-A | Sulfonyl pyridine amide derivatives and preparation method thereof | 杭州职业技术学院 | 2020-12-29 | — | — | CN | disclosed |