SCHEMBL28565855

SCHEMBL28565855

CCCCOC(=O)C(Cc1ccccc1)(CC(C)C)C(=O)OCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 2/20 0.47
RECQL P46063 1/20 0.40
TP53 P04637 1/20 0.40
MMP8 P22894 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CTSK P43235 2/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 3/20 0.39
PTPN1 P18031 2/20 0.39
PTPRC P08575 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31147053 0.96 TSHR (0.46) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28549749 0.92 LMNA (0.44) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28147414 0.89 TSHR (0.54) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28123749 0.87 ALDH1A1 (0.45) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL4416410 0.86 MMP8 (0.54) ALDH1A1L3MBTL1RECQLMMP8HSD17B10
SCHEMBL28123739 0.86 TSHR (0.51) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28004336 0.85 ALDH1A1 (0.52) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28123756 0.85 TSHR (0.50) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28123737 0.85 TSHR (0.50) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL28667908 0.84 TSHR (0.53) TSHRALDH1A1CYP3A4TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909171-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-109678996-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678998-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678997-B Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109679006-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-08-03 CN disclosed
CN-109679004-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed