Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022007 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTHSP90AB1HSD17B3 | |
| SCHEMBL2861743 | 0.84 | HSP90AB1 (0.39) | ALDH1A1HPGDHTTHSP90AB1ATM | |
| SCHEMBL16528479 | 0.79 | ANPEP (0.49) | ALDH1A1HTTHSP90AB1ANPEPDPP4 | |
| SCHEMBL2855027 | 0.79 | HTT (0.41) | ALDH1A1HPGDHTTHSP90AB1ATM | |
| SCHEMBL10886320 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTHSP90AB1ATM | |
| SCHEMBL2857757 | 0.76 | SRD5A2 (0.39) | ALDH1A1HPGDHTTMAPTSMN1; SMN2 | |
| SCHEMBL29531568 | 0.75 | ANPEP (0.49) | ALDH1A1HPGDHSP90AB1ANPEPDPP4 | |
| SCHEMBL7105504 | 0.75 | ANPEP (0.49) | ALDH1A1HPGDHSP90AB1ANPEPDPP4 | |
| SCHEMBL27564987 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTHSP90AB1ATM | |
| SCHEMBL2856590 | 0.74 | HTT (0.68) | ALDH1A1HPGDHTTHSP90AB1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| US-6924400-B2 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2005-08-02 | — | — | US | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| US-20030195259-A1 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-16 | — | — | US | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195259-A1 | Triaromatic vitamin D analogues | CYP24A1, CYP2R1, VDR | ALDH1A1 151/4885HPGD 85/4885HTT 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.