Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.75 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | ESR1 | P03372 | 1/20 | 0.75 |
| ▸ | TST | Q16762 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.68 |
| ▸ | VDR | P11473 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651547 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL29768278 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL5917328 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL5284953 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL285664 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL6651542 | 1.00 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1249402 | 0.92 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL18393817 | 0.92 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL31602211 | 0.92 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL19733279 | 0.92 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130244269-A1 | MEASURING LEVELS OF A METABOLITE | PERKINELMER HEALTH SCIENCES, INC. (US) | 2013-09-19 | — | — | US | claimed |
| US-8415162-B2 | Measuring levels of a metabolite | PERKINELMER HEALTH SCIENCES, INC. (US) | 2013-04-09 | — | — | US | claimed |
| US-20120295361-A1 | MEASURING LEVELS OF A METABOLITE | PERKINELMER HEALTH SCIENCES, INC. | 2012-11-22 | — | — | US | claimed |
| US-8257977-B2 | Measuring levels of a metabolite | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-09-04 | — | — | US | claimed |
| US-20110020942-A1 | MEASURING LEVELS OF A METABOLITE | PERKINELMER HEALTH SCIENCES, INC. | 2011-01-27 | — | — | US | claimed |
| US-20090137536-A1 | METHOD FOR TREATING AND PREVENTING HYPERPARATHYROIDISM | MAZESS RICHARD B | 2009-05-28 | — | — | US | claimed |
| EP-1499324-A4 | METHOD FOR TREATING AND PREVENTING HYPERPARATHYROIDISM | BONE CARE INT INC (US) | 2008-11-12 | — | — | EP | claimed |
| US-20070043005-A1 | TREATMENT OF HYPERPROLIFERATIVE DISEASES USING HIGH DOSES OF ACTIVE VITAMIN D | GENZYME CORPORATION (US) | 2007-02-22 | — | — | US | claimed |
| WO-2007006036-A2 | HYDROXYLATED FORMS OF ERGOSTEROLS AND ERGOCALCIFEROLS, DERIVATIVES THEREOF, METHODS OF PRODUCTION AND USES THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2007-01-11 | — | — | WO | claimed |
| US-7122530-B2 | 24-hydroxyvitamin D, analogs and uses thereof | GENZYME CORPORATION (US) | 2006-10-17 | — | — | US | claimed |
| EP-0614456-B1 | 1ALPHA,24(S)-DIHYDROXY VITAMIN D2, ITS FORMATION AND USE | BONE CARE INT INC (US) | 1999-06-09 | — | — | EP | claimed |
| EP-0914825-A2 | Methods for preparation of 1 alpha, 24-dihydroxy vitamin D2 | BONE CARE INTERNATIONAL, INC. (US) | 1999-05-12 | — | — | EP | claimed |
| EP-0614456-A4 | 1-g(a),24(S)-DIHYDROXY VITAMIN D 2?, ITS FORMATION AND USE. | LUNAR CORP (US) | 1995-01-04 | — | — | EP | claimed |
| EP-0614456-A1 | 1$g(a),24(S)-DIHYDROXY VITAMIN D 2?, ITS FORMATION AND USE | BONE CARE INTERNATIONAL, INC. (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0550702-A4 | METHODS FOR PREPARATION AND USE OF 1-G(A),24-DIHYDROXY VITAMIN D 2? | LUNAR CORP (US) | 1994-06-08 | — | — | EP | claimed |
| WO-1994005630-A1 | 1α,24(S)-DIHYDROXY VITAMIN D2, ITS FORMATION AND USE | LUNAR CORPORATION (US) | 1994-03-17 | — | — | WO | claimed |
| EP-0550702-A1 | METHODS FOR PREPARATION AND USE OF 1$g(a),24-DIHYDROXY VITAMIN D 2? | BONE CARE INTERNATIONAL, INC. (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992012165-A1 | METHODS FOR PREPARATION AND USE OF 1α,24-DIHYDROXY VITAMIN D¿2? | LUNAR CORPORATION (US) | 1992-07-23 | — | — | WO | claimed |
| EP-0077353-A1 | 1-HYDROXYLATION PROCESS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1983-04-27 | — | — | EP | claimed |
| WO-1982003864-A1 | 1-HYDROXYLATION PROCESS | WISCONSIN ALUMNI RES FOUND (US) | 1982-11-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137536-A1 | METHOD FOR TREATING AND PREVENTING HYPERPARATHYROIDISM | VDR, CYP27B1, PTH1R | ALDH1A1 740/4885ALOX15 960/4885CYP3A4 1969/4885 |
| US-20070043005-A1 | TREATMENT OF HYPERPROLIFERATIVE DISEASES USING HIGH DOSES OF ACTIVE VITAMIN D | VDR, CYP24A1, CYP27B1 | ALDH1A1 2114/4885ALOX15 407/4885CYP3A4 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.