Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162554 | 0.87 | DGAT1 (0.43) | MAOBMAPK8HTT | |
| SCHEMBL29162551 | 0.87 | DGAT1 (0.43) | MAOBMAPK8HTT | |
| SCHEMBL29162548 | 0.84 | TRPV4 (0.39) | — | |
| SCHEMBL29162550 | 0.84 | TRPV4 (0.39) | — | |
| SCHEMBL28948404 | 0.83 | TRPA1 (0.46) | MAOB | |
| SCHEMBL28566533 | 0.82 | OPRD1 (0.42) | ALDH1A1 | |
| SCHEMBL28566530 | 0.82 | OPRD1 (0.42) | ALDH1A1 | |
| SCHEMBL18039530 | 0.76 | MEN1 (0.41) | ALDH1A1 | |
| SCHEMBL28566499 | 0.76 | PARP10 (0.45) | MAOBALDH1A1 | |
| SCHEMBL375856 | 0.76 | SRR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480116-B | PKB inhibitors | 南京正大天晴制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112480116-A | PKB inhibitors | 南京正大天晴制药有限公司 | 2021-03-12 | — | — | CN | disclosed |