Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585171 | 0.96 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL23268445 | 0.90 | APP (0.35) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL28561422 | 0.90 | APP (0.38) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL20636821 | 0.90 | CA12 (0.38) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL29774219 | 0.90 | APP (0.41) | APPCA12CA1CA9LMNA | |
| SCHEMBL7211715 | 0.90 | APP (0.41) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL14750206 | 0.90 | APP (0.41) | APPCA12CA1CA9LMNA | |
| Ammonia Solution, Strong SCHEMBL23795736 | 0.88 | APP (0.37) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL17832917 | 0.86 | CA12 (0.35) | ALDH1A1SMN1; SMN2APPCA12CA1 | |
| SCHEMBL16396048 | 0.85 | LMNA (0.40) | ALDH1A1SMN1; SMN2CA1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112592459-B | Polyisocyanate composition, coating composition and coated substrate | 旭化成株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-112592459-A | Polyisocyanate composition, coating composition and coated substrate | 旭化成株式会社 | 2021-04-02 | — | — | CN | disclosed |