Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062763 | 1.00 | TSHR (0.58) | TSHRMAPK1RECQLL3MBTL1ATM | |
| SCHEMBL5370477 | 0.87 | TSHR (0.71) | TSHRMAPK1RECQLL3MBTL1ATM | |
| SCHEMBL5372898 | 0.86 | SMN1; SMN2 (0.71) | TSHRMAPK1RECQLL3MBTL1ATM | |
| SCHEMBL11192277 | 0.85 | TSHR (0.68) | TSHRMAPK1RECQLL3MBTL1SMN1; SMN2 | |
| SCHEMBL30062502 | 0.84 | LMNA (0.63) | TSHRRECQLL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL28572264 | 0.84 | LMNA (0.63) | TSHRRECQLL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9348025 | 0.83 | LMNA (0.58) | MAPK1L3MBTL1ATMTP53POLB | |
| SCHEMBL11201529 | 0.82 | MAPT (0.66) | TSHRMAPK1RECQLL3MBTL1SMN1; SMN2 | |
| SCHEMBL5379370 | 0.82 | TSHR (0.65) | TSHRMAPK1RECQLL3MBTL1SMN1; SMN2 | |
| SCHEMBL7497251 | 0.82 | MEN1 (0.68) | TSHRL3MBTL1ATMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898207-B | Compound and preparation method and application thereof | 中国海洋石油集团有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-112898207-A | Compound and preparation method and application thereof | 中国海洋石油集团有限公司 | 2021-06-04 | — | — | CN | disclosed |