Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560875 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL12446486 | 0.71 | GFER (0.34) | — | |
| SCHEMBL10442596 | 0.71 | HCAR2 (0.46) | ADORA2AHCAR2PDE10A | |
| SCHEMBL28570271 | 0.69 | PDPK1 (0.41) | ADORA2AHCAR2 | |
| SCHEMBL16502279 | 0.69 | PDE10A (0.44) | ADORA2APDE10A | |
| SCHEMBL28567385 | 0.68 | RAB9A (0.41) | — | |
| SCHEMBL14041780 | 0.68 | GAA (0.43) | — | |
| SCHEMBL28572537 | 0.68 | DYRK1A (0.34) | — | |
| SCHEMBL13325291 | 0.67 | NOS1 (0.41) | ADORA2AHCAR2 | |
| SCHEMBL2642889 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |