SCHEMBL28566932

SCHEMBL28566932

NBr.NC(=O)CCC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.31
BLM P54132 2/20 0.31
PMP22 Q01453 2/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL429299 0.95
Hydrochloric Acid SCHEMBL6594522 0.92 ALOX15 (0.32) ALOX15BLMPMP22KMT2AMCL1
SCHEMBL377071 0.81 FAAH (0.32) ALOX15BLMPMP22KMT2AKDM4E
SCHEMBL1766736 0.79 FAAH (0.35) ALOX15KMT2AKDM4ETP53CYP1A2
Hydrochloric Acid SCHEMBL376782 0.79 KMT2A (0.31) ALOX15BLMPMP22KMT2AKDM4E
SCHEMBL24096259 0.77 FAAH (0.39) PMP22KMT2AKDM4ELMNATP53
Hydrochloric Acid SCHEMBL5707326 0.77 FAAH (0.34) ALOX15BLMKMT2AKDM4ETP53
SCHEMBL4439060 0.74 CA1 (0.33) ALOX15BLMPMP22KMT2AKDM4E
SCHEMBL9282824 0.74
SCHEMBL1030177 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109529057-B Calcium ion response dual-mode magnetic resonance imaging probe and preparation method thereof 厦门大学 2021-04-16 CN claimed
CN-109529057-B Calcium ion response dual-mode magnetic resonance imaging probe and preparation method thereof 厦门大学 2021-04-16 CN disclosed
CN-109529057-B Calcium ion response dual-mode magnetic resonance imaging probe and preparation method thereof 厦门大学 2021-04-16 CN disclosed