⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6594522 | 0.97 | ALOX15 (0.32) | — | |
| SCHEMBL28566932 | 0.95 | ALOX15 (0.31) | — | |
| SCHEMBL377071 | 0.86 | FAAH (0.32) | — | |
| SCHEMBL1766736 | 0.83 | FAAH (0.35) | — | |
| Hydrochloric Acid SCHEMBL376782 | 0.83 | KMT2A (0.31) | — | |
| SCHEMBL24096259 | 0.81 | FAAH (0.39) | — | |
| Hydrochloric Acid SCHEMBL5707326 | 0.81 | FAAH (0.34) | — | |
| SCHEMBL4439060 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL1030177 | 0.78 | — | — | |
| SCHEMBL29887024 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504785-A1 | DR5 AGONIST AND PLK1 INHIBITOR OR CDK INHIBITOR COMBINATION THERAPY | Inhibrx Biosciences, Inc. (US) | 2025-02-12 | — | — | EP | claimed |
| EP-4499097-A1 | METHODS OF TREATING A SUBJECT FOR POST-TREATMENT LYME DISEASE (PTLD) AND COMPOSITIONS FOR USE IN THE SAME | IncellDx, Inc. (US) | 2025-02-05 | — | — | EP | claimed |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | claimed |
| WO-2023196943-A1 | DR5 AGONIST AND PLK1 INHIBITOR OR CDK INHIBITOR COMBINATION THERAPY | Inhibrx, Inc. (US) | 2023-10-12 | — | — | WO | claimed |
| WO-2023192360-A1 | METHODS OF TREATING A SUBJECT FOR POST-TREATMENT LYME DISEASE (PTLD) AND COMPOSITIONS FOR USE IN THE SAME | INCELLDX, INC. (US) | 2023-10-05 | — | — | WO | claimed |
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | claimed |
| CN-110372492-B | Method for synthesizing cinacalcet hydrochloride intermediate by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2022-09-20 | — | — | CN | claimed |
| US-20210061775-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2021-03-04 | — | — | US | claimed |
| CN-108884096-A | Spiral shell dihydroindolone as DDR1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-11-23 | — | — | CN | claimed |
| US-20180155301-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2018-06-07 | — | — | US | claimed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| CN-101208336-A | Thiazolidinones free of basic nitrogen, their preparation and use as pharmaceutical agents | SCHERING AG (DE) | 2008-06-25 | — | — | CN | claimed |
| CN-101208094-A | Pharmacokinetic improved compounds | SURFACE LOGIX INC (US) | 2008-06-25 | — | — | CN | claimed |
| CN-100374115-C | Substituted diketopiperazines as oxytocin antagonists | GLAXO GROUP LTD (GB) | 2008-03-12 | — | — | CN | claimed |
| CN-1606443-A | Substituted diketopiperazines as oxytocin antagonists | GLAXO GROUP LTD (GB) | 2005-04-13 | — | — | CN | claimed |
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |
| CN-1223656-A | Spiro-piperidine derivatives and their use as therapeutic agents | MERCK SHARP & DOHME (GB) | 1999-07-21 | — | — | CN | claimed |
| CN-1133844-A | Osa-or thia-aliphatically bridged quinoxaline-2,3-diones | CIBA GEIGY AG (CH) | 1996-10-23 | — | — | CN | claimed |