Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 15/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.49 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.49 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464270 | 0.90 | XDH (0.64) | XDHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28568979 | 0.90 | XDH (0.64) | XDHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28432409 | 0.89 | XDH (0.67) | XDHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL30464263 | 0.85 | XDH (0.70) | XDHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28570831 | 0.85 | XDH (0.70) | XDHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28566556 | 0.85 | XDH (0.69) | XDHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30464269 | 0.85 | XDH (0.69) | XDHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30464267 | 0.84 | XDH (0.73) | XDH | |
| SCHEMBL28572802 | 0.84 | XDH (0.73) | XDH | |
| SCHEMBL28571559 | 0.84 | XDH (0.71) | XDHPFKFB2PFKFB1PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920170-A | N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112920170-B | N- (indol-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112920170-A | N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | disclosed |