Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.48 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464270 | 1.00 | XDH (0.64) | XDHALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28567262 | 0.90 | XDH (0.66) | XDHALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28432409 | 0.89 | XDH (0.67) | XDHALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28566556 | 0.87 | XDH (0.69) | XDHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL30464269 | 0.87 | XDH (0.69) | XDHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL28569043 | 0.86 | XDH (0.68) | XDHALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30464260 | 0.86 | XDH (0.68) | XDHALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30464267 | 0.84 | XDH (0.73) | XDH | |
| SCHEMBL28572802 | 0.84 | XDH (0.73) | XDH | |
| SCHEMBL28430809 | 0.84 | XDH (0.65) | XDHALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920170-A | N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112920170-B | N- (indol-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112920170-A | N- (indole-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | disclosed |