Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257938 | 0.89 | DGKA (0.56) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9333754 | 0.83 | KDM4E (0.40) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28152436 | 0.82 | TSHR (0.52) | FAAHCYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL11117446 | 0.82 | KDM4E (0.41) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28367146 | 0.81 | KDM4E (0.39) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL3716635 | 0.81 | DGKA (0.43) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL14945 | 0.80 | LMNA (0.43) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28359681 | 0.80 | DGKA (0.38) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28667284 | 0.80 | KDM4E (0.38) | DGKAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28041960 | 0.79 | CYP2D6 (0.39) | DGKAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812307-A | Single-end-capped amphiphilic organosiloxane macromonomer, silicone hydrogel, corneal contact lens and preparation method | 江苏海伦隐形眼镜有限公司 | 2021-05-18 | — | — | CN | disclosed |