Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245217 | 0.85 | LCK (0.57) | TUBB4ATUBBTUBA3CARTUBA1B | |
| SCHEMBL14092524 | 0.81 | PLK4 (0.60) | MAPTLRRK2MAOAMAOB | |
| SCHEMBL14092536 | 0.79 | LRRK2 (0.71) | LRRK2MAOAMAOB | |
| SCHEMBL4135006 | 0.77 | CYP19A1 (0.57) | ALPICYP19A1CYP11B2MEN1KMT2A | |
| SCHEMBL5474689 | 0.77 | PLK4 (0.72) | TP53CYP1A2MEN1ALDH1A1MAPT | |
| SCHEMBL4725013 | 0.77 | PLK4 (0.72) | TP53CYP1A2MEN1ALDH1A1MAPT | |
| SCHEMBL5474682 | 0.77 | PLK4 (0.72) | TP53CYP1A2MEN1ALDH1A1MAPT | |
| SCHEMBL14092189 | 0.77 | CYP1A2 (0.45) | TUBB4ATUBBTUBA3CARTUBA1B | |
| SCHEMBL28640571 | 0.76 | ALDH1A1 (0.50) | TUBB4ATUBBTUBA3CARTUBA1B | |
| SCHEMBL3816595 | 0.76 | LRRK2 (0.57) | ARCYP1A2CYP19A1CYP11B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480394-A | Green synthesis method of alkylene fluorene | 温州大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-109651049-B | Benzo (b) fluoranthene derivative and preparation method thereof | 石河子大学 | 2021-05-18 | — | — | CN | disclosed |