SCHEMBL4135006

SCHEMBL4135006

Clc1ccc(C=C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.57
CYP11B2 P19099 2/20 0.57
MAOB P27338 4/20 0.47
MAOA P21397 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
ALPL P05186 1/20 0.42
ALPI P09923 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ELANE P08246 1/20 0.41
LRRK2 Q5S007 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30381697 0.81 LCK (0.56) MAOBMAOASIRT1ALPLALPI
SCHEMBL3372898 0.81 LCK (0.56) MAOBMAOASIRT1ALPLALPI
SCHEMBL283216 0.80 CYP19A1 (0.67) CYP19A1CYP11B2MAOBMAOAMEN1
SCHEMBL4541307 0.78 CYP19A1 (0.62) CYP19A1CYP11B2MAOBMAOAMEN1
SCHEMBL19784873 0.77 CYP19A1 (0.57) CYP19A1CYP11B2ALPLALPIKMT2A
SCHEMBL28641189 0.77 PARP1 (0.62) CYP19A1CYP11B2ALPLALPI
SCHEMBL1225662 0.77 CYP19A1 (0.57) CYP19A1CYP11B2SIRT1MEN1KMT2A
SCHEMBL11803759 0.77 CYP19A1 (0.57) CYP19A1CYP11B2MEN1KMT2AL3MBTL1
SCHEMBL17762732 0.77 MAPT (0.55) MAOBMAOA
SCHEMBL3816595 0.77 LRRK2 (0.57) CYP19A1CYP11B2MAOBSIRT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480394-A Green synthesis method of alkylene fluorene 温州大学 2021-10-08 CN disclosed
CN-109651049-B Benzo (b) fluoranthene derivative and preparation method thereof 石河子大学 2021-05-18 CN disclosed
US-7479357-B2 Substituted 9H-fluorenone hydrazones SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-01-20 US disclosed
EP-1283448-B1 Electrophotographic organophotoreceptors with charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2008-11-05 EP disclosed
EP-1293837-B1 Electrophotographic organophotoreceptors SAMSUNG ELECTRONICS CO LTD (KR) 2008-10-08 EP disclosed
US-7358014-B2 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-15 US disclosed
US-7291431-B2 Organophotoreceptor with charge transport compound having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US disclosed
EP-1530096-B1 Organophotoreceptor with a hydrazone polymer charge transport material SAMSUNG ELECTRONICS CO LTD (KR) 2007-06-20 EP disclosed
US-7202004-B2 Charge transport compound containing at least two carbazolecarboxaldehyde substituted- hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-10 US disclosed
EP-1418469-B1 Organophotoreceptor with charge transport compound with hydrazone groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-04-04 EP disclosed
US-20030215728-A1 Hydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2003-11-20 US disclosed
US-20030207188-A1 Carbazole based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2003-11-06 US disclosed
US-20030198880-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-10-23 US disclosed
EP-1335250-A1 Electrophotographic organophotoreceptors with novel charge transport materials Samsung Electronics Co., Ltd. (KR) 2003-08-13 EP disclosed
US-20030113643-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-06-19 US disclosed
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG INFORMATION SYSTEMS AMERICA 2003-06-19 US disclosed
US-20030104294-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-06-05 US disclosed
EP-1298496-A2 Electrophotographic organophotoreceptors SAMSUNG ELECTRONICS Co. Ltd. (KR) 2003-04-02 EP disclosed
EP-1293837-A2 Electrophotographic organophotoreceptors Samsung Electronics Co., Ltd. (KR) 2003-03-19 EP disclosed
EP-1283448-A2 Electrophotographic organophotoreceptors with charge transport compounds Samsung Electronics Co., Ltd. (KR) 2003-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207188-A1 Carbazole based charge transport compounds SLC33A1, SLC43A1, AHR CYP19A1 502/4885CYP11B2 34/4885MAOB 1714/4885
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SLC43A1, SLC18A2, SLC1A1 CYP19A1 1974/4885CYP11B2 920/4885MAOB 760/4885
US-20030215728-A1 Hydrazone-based charge transport compounds SLC9A1, SLC9A2, SLC26A4 CYP19A1 406/4885CYP11B2 21/4885MAOB 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.