SCHEMBL28567745

SCHEMBL28567745

CCCCC(C)(Oc1ccc(O)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.49
TSHR P16473 2/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
MAPK1 P28482 1/20 0.49
CYP2C19 P33261 1/20 0.49
NR1H2 P55055 1/20 0.49
RNASEL Q05823 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NR5A1 Q13285 1/20 0.49
LTA4H P09960 2/20 0.46
ESR2 Q92731 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
HSD17B3 P37058 2/20 0.45
TP53 P04637 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5531801 0.92 ADORA3 (0.47) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL4550641 0.89 PPARA (0.54) TSHRLTA4HADORA3PPARGPPARA
SCHEMBL5369095 0.85 ADORA3 (0.60) ESR1CYP1A2CYP2D6CYP2C19ESR2
SCHEMBL5141872 0.85 ADORA3 (0.60) ESR1CYP1A2CYP2D6CYP2C19ESR2
SCHEMBL5367947 0.85 ADORA3 (0.60) ESR1CYP1A2CYP2D6CYP2C19ESR2
SCHEMBL3966243 0.84 PPARA (0.52) TSHRLTA4HADORA3PPARGPPARA
SCHEMBL10712455 0.83 ADORA3 (0.43) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL29129794 0.83 PPARG (0.51) TSHRPPARGPPARATP53PSEN1
SCHEMBL10975149 0.82 PPARG (0.55) ESR1ESR2PPARGPPARA
SCHEMBL28845860 0.80 S1PR4 (0.48) TSHRPPARGPPARATP53PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109867601-B Preparation method of (R) -2- (4-hydroxyphenoxy) butyl propionate 湖南速博生物技术有限公司 2021-05-28 CN disclosed