Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129794 | 0.98 | PPARG (0.51) | PPARAPPARGTP53TSHRPLA2G4B | |
| SCHEMBL4550641 | 0.95 | PPARA (0.54) | PPARAPPARGTP53TSHRLTA4H | |
| SCHEMBL8935937 | 0.88 | PPARG (0.53) | PPARAPPARGADORA3 | |
| SCHEMBL82055 | 0.88 | PPARG (0.53) | PPARAPPARGADORA3 | |
| SCHEMBL28489847 | 0.87 | PPARG (0.52) | PPARAPPARGPSEN1PSEN2APH1B | |
| SCHEMBL28845860 | 0.86 | S1PR4 (0.48) | PPARAPPARGTP53TSHRPLA2G4B | |
| SCHEMBL28567745 | 0.84 | ESR1 (0.49) | PPARAPPARGTP53TSHRLTA4H | |
| SCHEMBL5508342 | 0.82 | PPARA (0.46) | PPARAPPARGTP53TSHRLTA4H | |
| SCHEMBL9417313 | 0.81 | PPARA (0.53) | PPARAPPARGADORA3 | |
| SCHEMBL1960387 | 0.81 | PPARG (0.62) | PPARAPPARGADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083717-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2021-08-10 | — | — | US | claimed |
| CN-113056198-A | Herbicidal combination | UPL有限公司 | 2021-06-29 | — | — | CN | claimed |
| EP-3659597-A2 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2020-06-03 | — | — | EP | claimed |
| US-20200138796-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2020-05-07 | — | — | US | claimed |
| WO-2020039366-A1 | HERBICIDAL COMBINATION | UPL LTD (IN) | 2020-02-27 | — | — | WO | claimed |
| US-10543200-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2020-01-28 | — | — | US | claimed |
| US-20190314381-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | THE TEXAS A&M UNIVERSITY SYSTEM | 2019-10-17 | — | — | US | claimed |
| US-20180243275-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2018-08-30 | — | — | US | claimed |
| EP-3340979-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2018-07-04 | — | — | EP | claimed |
| US-20170065601-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-03-09 | — | — | US | claimed |
| WO-2017035438-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-03-02 | — | — | WO | claimed |
| EP-3110415-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2017-01-04 | — | — | EP | claimed |
| WO-2015131019-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-09-03 | — | — | WO | claimed |
| EP-1585392-B1 | HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. | YISSUM RES DEV CO (IL) | 2009-03-18 | — | — | EP | claimed |
| US-20060039943-A1 | Acetyl-CoA carboxylase inhibitors for use as pesticides | Yissum Research Development Company fo the Hebrew University (IL) | 2006-02-23 | — | — | US | claimed |
| EP-1585392-A2 | HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-10-19 | — | — | EP | claimed |
| WO-2004060058-A2 | HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-07-22 | — | — | WO | claimed |
| EP-0756632-A1 | PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME | ZENECA LIMITED (GB) | 1997-02-05 | — | — | EP | claimed |
| WO-1995029246-A1 | PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME | ZENECA LIMITED (GB) | 1995-11-02 | — | — | WO | claimed |
| WO-1994023027-A2 | PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180243275-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | ABCC1, SLC11A2, CYP3A43 | PPARA 2452/4885PPARG 2557/4885TP53 2587/4885 |
| US-20190314381-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | ME3, PGLS, GNPAT | PPARA 396/4885PPARG 281/4885TP53 496/4885 |
| US-20200138796-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | ABCC1, SLC11A2, ABCG2 | PPARA 2384/4885PPARG 2475/4885TP53 2207/4885 |
| US-10543200-B2 | Compositions and methods for drug sensitization of parasites | ABCC1, SLC11A2, ABCG2 | PPARA 2384/4885PPARG 2475/4885TP53 2207/4885 |
| US-11083717-B2 | Compositions and methods for drug sensitization of parasites | ABCC1, SLC11A2, ABCG2 | PPARA 2384/4885PPARG 2475/4885TP53 2207/4885 |
| US-20170065601-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF MYCOBACTERIA | ME3, PGLS, GNPAT | PPARA 396/4885PPARG 281/4885TP53 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.