SCHEMBL28568680

SCHEMBL28568680

CN1CCN(CCCCNc2cccc3c2C(=O)c2nccc4ccnc-3c24)CC1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.46
SRC P12931 4/20 0.46
EGFR P00533 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28611047 0.92 FGFR1 (0.46) FGFR1SRCEGFR
SCHEMBL28582968 0.91 S100A4 (0.51)
SCHEMBL28606726 0.83 S100A4 (0.51)
SCHEMBL28569309 0.80 TERT (0.53) FGFR1SRCEGFR
SCHEMBL28588007 0.73 TERT (0.68)
SCHEMBL11688654 0.68 TERT (0.61) EGFR
SCHEMBL11689938 0.67 NQO1 (0.65) FGFR1SRCEGFR
SCHEMBL7063150 0.66 MAPT (0.53) EGFR
SCHEMBL28578814 0.66 TERT (0.51)
SCHEMBL28594887 0.65 TERT (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438445-B 8-substituted 1, 6-diazabenzanthrone derivative and synthesis method and application thereof GUANGXI NORMAL UNIVERSITY (CN) 2021-06-22 CN disclosed