Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579819 | 0.85 | XDH (0.55) | XDHMCL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28574650 | 0.81 | XDH (0.52) | XDHKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL28577383 | 0.81 | XDH (0.52) | XDHNR1H4MMP2MMP3 | |
| SCHEMBL28589437 | 0.80 | ALDH1A1 (0.61) | XDHNR1H4KMT2AMEN1TARBP2 | |
| SCHEMBL28570867 | 0.80 | XDH (0.59) | XDHKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL28580883 | 0.76 | PDE2A (0.44) | XDH | |
| SCHEMBL28579822 | 0.76 | XDH (0.53) | XDHMCL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28582832 | 0.75 | MCL1 (0.37) | XDHNR1H4MDM2MCL1KMT2A | |
| SCHEMBL28914640 | 0.74 | XDH (0.47) | XDHKMT2AMEN1SMN1; SMN2MMP2 | |
| SCHEMBL27795558 | 0.73 | TARBP2 (0.73) | XDHNR1H4KMT2ATARBP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | disclosed |