Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 12/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574650 | 0.83 | XDH (0.52) | XDHRARBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28589918 | 0.81 | XDH (0.56) | XDHMAPK1RARBKDM4EALDH1A1 | |
| SCHEMBL28587007 | 0.80 | NPC1 (0.68) | XDHMAPK1RARBKDM4EALDH1A1 | |
| SCHEMBL28570870 | 0.80 | XDH (0.54) | XDHKDM4EALDH1A1 | |
| SCHEMBL28569175 | 0.80 | XDH (0.55) | XDHSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL28579819 | 0.78 | XDH (0.55) | XDHKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28579822 | 0.78 | XDH (0.53) | XDHKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28914640 | 0.74 | XDH (0.47) | XDHKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28583439 | 0.71 | XDH (0.61) | XDH | |
| SCHEMBL34461785 | 0.70 | XDH (0.56) | XDHKDM4EALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | disclosed |