Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104769 | 0.83 | PTPN1 (0.43) | MAPTTHRB | |
| SCHEMBL31298110 | 0.83 | PTPN1 (0.43) | MAPTTHRB | |
| SCHEMBL5373635 | 0.76 | PTPN1 (0.54) | CSNK2A2CSNK2BCSNK2A1POLBALDH1A1 | |
| SCHEMBL28567067 | 0.75 | CES1 (0.42) | POLBALDH1A1KMT2ATDP1MAPT | |
| SCHEMBL11551282 | 0.75 | ALDH1A1 (0.59) | CSNK2A2CSNK2BCSNK2A1POLBALDH1A1 | |
| SCHEMBL11620092 | 0.75 | MAOB (0.46) | CSNK2A2CSNK2BCSNK2A1POLBALDH1A1 | |
| SCHEMBL27313609 | 0.74 | KDM4E (0.38) | CSNK2A2CSNK2BCSNK2A1ALDH1A1MAPT | |
| SCHEMBL17522055 | 0.71 | KMT2A (0.59) | POLBALDH1A1KMT2ATDP1MAPT | |
| SCHEMBL27700653 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTTHRBCYP3A4CYP2C19 | |
| SCHEMBL17876373 | 0.70 | PTPN1 (0.45) | POLBALDH1A1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406075-A | Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof | 遵义医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114560838-B | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-112898256-B | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113149948-B | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114560838-A | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113149948-A | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-112898256-A | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2021-06-04 | — | — | CN | disclosed |