Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313611 | 0.80 | ATM (0.35) | CSNK2A2CSNK2BCSNK2A1NUDT1RAPGEF4 | |
| SCHEMBL16648836 | 0.77 | CYP3A4 (0.39) | KDM4EALDH1A1TSHRMAPK1KCNA3 | |
| SCHEMBL23241836 | 0.76 | AR (0.35) | KDM4ETSHRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL28569245 | 0.74 | CSNK2A2 (0.37) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL11538950 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11549214 | 0.73 | PSMB5 (0.44) | KDM4ECSNK2A2CSNK2BCSNK2A1NUDT1 | |
| SCHEMBL18493268 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHRMAPK1KCNA3 | |
| SCHEMBL16707578 | 0.72 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1NUDT1RAPGEF4 | |
| SCHEMBL11540145 | 0.72 | ALOX15 (0.36) | ALDH1A1TSHRMAPK1CSNK2A2CSNK2B | |
| SCHEMBL11620092 | 0.70 | MAOB (0.46) | ALDH1A1TSHRCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | MEDSHINE DISCOVERY INC. (CN) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | CYP3A7, UGT2B7, CYP51A1 | KDM4E 902/4885ALDH1A1 1326/4885TSHR 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.