Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367620 | 0.89 | PAOX (0.48) | PAOXMAOAMAOBTP53HDAC6 | |
| SCHEMBL8953972 | 0.84 | MAOA (0.40) | PAOXMAOAMAOBHDAC6KDM4E | |
| Octadecanoic Acid Amide SCHEMBL368172 | 0.83 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Diethanolamine SCHEMBL6763687 | 0.83 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Diethanolamine SCHEMBL28070607 | 0.83 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL3134640 | 0.81 | — | — | |
| Diethanolamine SCHEMBL27378824 | 0.81 | SOAT1 (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL28343626 | 0.79 | MAOA (0.31) | MAOAMAOBMEN1TP53KMT2A | |
| Octadecanoic Acid Amide SCHEMBL11883762 | 0.79 | SOAT1 (0.50) | PAOXSOAT1MEN1FAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL8198428 | 0.79 | SOAT1 (0.50) | PAOXSOAT1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112873526-A | Cutting process of aerated concrete plate | 安徽省高迪循环经济产业园股份有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-112873526-A | Cutting process of aerated concrete plate | 安徽省高迪循环经济产业园股份有限公司 | 2021-06-01 | — | — | CN | disclosed |