Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL6763687 | 1.00 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Diethanolamine SCHEMBL28070607 | 1.00 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Diethanolamine SCHEMBL27378824 | 0.98 | SOAT1 (0.52) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL8198428 | 0.94 | SOAT1 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL11883762 | 0.94 | SOAT1 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| Stearic Acid SCHEMBL8816310 | 0.93 | GPR84 (0.59) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| Diethanolamine SCHEMBL28705331 | 0.91 | NAAA (0.49) | SOAT1MEN1KMT2AFAAHTP53 | |
| Oleamide SCHEMBL69329 | 0.90 | FAAH (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| Oleamide SCHEMBL69330 | 0.90 | FAAH (0.74) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL27548471 | 0.90 | SOAT1 (0.46) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1077 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562772-B1 | Shampoo based on a detergent surfactant, a nacreous and/or opacifying agent and an acrylic terpolymer | L'OREAL (FR) | 2003-05-13 | — | — | US | claimed |
| EP-1152735-A1 | COSMETIC COMPOSITIONS CONTAINING A QUATERNARY SILICON AND A PEARLING AGENT AND THEIR USES | L'OREAL (FR) | 2001-11-14 | — | — | EP | claimed |
| WO-2001041719-A1 | COSMETIC COMPOSITIONS CONTAINING A QUATERNARY SILICON AND A PEARLING AGENT AND THEIR USES | L'OREAL (FR) | 2001-06-14 | — | — | WO | claimed |
| EP-1090623-A1 | A washing composition for keratinous materials based on a surfactant, an opacifying or pearlescent agent and a acrylic terpolymer | L'OREAL (FR) | 2001-04-11 | — | — | EP | claimed |
| EP-0582363-B1 | A thermosetting powder coating composition | INVENTA AG (CH) | 1997-06-04 | — | — | EP | claimed |
| US-5346960-A | Reactable mixture of carboxy acid containing acrylic, beta-hydroxyalkylamide curative and fatty acid hydroxyalkylamide; industrial metal coatings | ROHM AND HAAS COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| EP-0582363-A1 | A thermosetting powder coating composition | ROHM AND HAAS COMPANY (US) | 1994-02-09 | — | — | EP | claimed |
| US-5216090-A | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM AND HAAS COMPANY (US) | 1993-06-01 | — | — | US | claimed |
| US-12042775-B2 | Consumer product comprising biodegradable delivery particles | THE PROCTER & GAMBLE COMPANY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240238191-A1 | PERSONAL CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2024-07-18 | — | — | US | disclosed |
| EP-4072684-B1 | HAIR STRENGTHENING COMPOSITION | PROCTER & GAMBLE (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20240207167-A1 | COMPOSITE OPACIFIER DISPERSION | DOW SILICONES CORP (US) | 2024-06-27 | — | — | US | disclosed |
| CN-115427008-B | Hair care formulation | 罗门哈斯公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115315243-B | Hair cleaning agent | 罗门哈斯公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-0582363-A1 | A thermosetting powder coating composition | ROHM AND HAAS COMPANY (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5216090-A | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM AND HAAS COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1993003703-A2 | HAIR SPRAY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1992021319-A1 | HAIR STYLING AGENTS AND COMPOSITIONS CONTAINING HYDROPHOBIC HAIR STYLING POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1988001876-A1 | POST-FOAMING GEL CONTAINING CERTAIN DIALKANOLAMIDE OR MONOALKANOLAMIDE | S.C. JOHNSON & SON, INC. (US) | 1988-03-24 | — | — | WO | disclosed |
| EP-0259843-A2 | Post-foaming gel with an unsaturated or non-linear dialkanolamide or a monoalkanolamide | S.C. JOHNSON & SON, INC. (US) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238191-A1 | PERSONAL CARE COMPOSITION | CUTA, POLR1C, POLN | SOAT1 57/4885MEN1 3865/4885KMT2A 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.