SCHEMBL28569798

SCHEMBL28569798

[c]1ccc(-c2cccnc2)c2occc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 0.41
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 4/20 0.41
CYP1A2 P05177 2/20 0.41
TDO2 P48775 1/20 0.40
CYP2C9 P11712 3/20 0.39
CYP2B6 P20813 3/20 0.39
CYP2C19 P33261 3/20 0.39
TSHR P16473 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNA5 P30532 1/20 0.37
CHRNA4 P43681 1/20 0.37
NUDT1 P36639 1/20 0.37
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21300575 0.80 CHRM2 (0.33)
SCHEMBL21295823 0.77 CYP2A6 (0.42) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL21295780 0.76 NUDT1 (0.43) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL21295784 0.74 ALDH1A1 (0.42) CYP2A6ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL21297628 0.71 ALDH1A1 (0.42) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL28575310 0.70 CYP2A6 (0.50) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL21295641 0.69 CYP11B1 (0.42) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL24318703 0.68 CYP2A6 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL21295725 0.68 ALDH1A1 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2TDO2
SCHEMBL21295856 0.67 CYP2A6 (0.41) CYP2A6ALDH1A1CYP3A4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed