Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23220354 | 0.89 | RAB9A (0.58) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL23220335 | 0.83 | NPC1 (0.64) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL28577342 | 0.81 | GUSB (0.73) | ALDH1A1KDM4ERAB9ANPC1RXFP1 | |
| SCHEMBL28569835 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL1346538 | 0.81 | RAB9A (0.51) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11666704 | 0.79 | RAB9A (0.59) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL12015939 | 0.78 | NPC1 (0.73) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL28573287 | 0.78 | PIK3CD (0.60) | KDM4ERAB9ANPC1RXFP1MEN1 | |
| SCHEMBL6155925 | 0.76 | GUSB (0.70) | ALDH1A1KDM4ERAB9ANPC1RXFP1 | |
| SCHEMBL28574645 | 0.75 | HDAC6 (0.61) | ALDH1A1KDM4ERAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |