Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155925 | 0.88 | GUSB (0.70) | GUSBHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23220354 | 0.88 | RAB9A (0.58) | GUSBHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23220335 | 0.82 | NPC1 (0.64) | GUSBHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28569834 | 0.81 | ALDH1A1 (0.54) | GUSBALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL28569835 | 0.80 | ALDH1A1 (0.55) | GUSBALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1346538 | 0.80 | RAB9A (0.51) | GUSBHPGDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL11666704 | 0.78 | RAB9A (0.59) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL12015939 | 0.77 | NPC1 (0.73) | HPGDALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL28571808 | 0.77 | RAB9A (0.59) | GUSBHPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL21065048 | 0.75 | ALDH1A1 (0.62) | GUSBHPGDALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |